Netflix's 'Cold Case: The Tylenol Murders': Inside the Chilling Unsolved Poisonings
Explore Netflix's gripping documentary Cold Case: The Tylenol Murders, revisiting the terrifying 1982 cyanide-laced Tylenol poisonings. Uncover suspects, theories, and new evidence in this haunting true-crime mystery.
Faheem Hassan
5/27/20252 min read


Unsealing the Mystery: Netflix's 'Cold Case: The Tylenol Murders' Reexamines a Chilling 1982 CrimeNew York Post+1ABC7 Chicago+1
On May 26, 2025, Netflix premiered Cold Case: The Tylenol Murders, a gripping three-part docuseries that delves into one of America's most unsettling unsolved crimes. Directed by Yotam Guendelman and Ari Pines, and executive produced by Joe Berlinger, the series revisits the 1982 Chicago-area poisonings where seven individuals died after ingesting cyanide-laced Tylenol capsules. NetflixPrime Video+11The Guardian+11Sportskeeda+11
The Crime That Changed Consumer Safety
In September 1982, seven people in the Chicago area, including 12-year-old Mary Kellerman, died suddenly after consuming Extra Strength Tylenol capsules that had been tampered with and laced with potassium cyanide. The victims included members of the Janus family, Mary McFarland, Mary Reiner, and Paula Prince. The random nature of the deaths and the everyday nature of the product led to nationwide panic, resulting in a massive recall of 25-30 million bottles and significant changes in pharmaceutical packaging standards. Prime Video+11Wikipedia+11Mix 1049+11The Sun+1The Guardian+1
A Suspect Without Conviction
The series spotlights James William Lewis, who sent an extortion letter to Johnson & Johnson demanding $1 million to stop the killings. Although Lewis was convicted of extortion and served 10 years in prison, he was never charged with the murders. The documentary features Lewis's final interview before his death in 2023, providing insight into his erratic behavior and the ongoing suspicion surrounding him. Sportskeeda+6Wikipedia+6The Sun+6New York Post+5The Sun+5Wikipedia+5New York Post
Exploring Alternative Theories
Beyond focusing on Lewis, the docuseries examines other theories, including the possibility of corporate involvement. It highlights the presence of cyanide at Johnson & Johnson's manufacturing plants and discusses a 1986 case where a woman died after ingesting a cyanide-laced Tylenol capsule, even after safety seals were implemented. Netflix+6Time+6The Guardian+6
A Call for Renewed Investigation
Cold Case: The Tylenol Murders not only recounts the events of 1982 but also aims to shed new light on the case through overlooked evidence and testimonies. The directors hope that the renewed attention and unsealing of long-hidden documents may finally lead to justice and closure for the victims and their families. Mix 1049+5Netflix+5Sportskeeda+5New York Post
Watch Now
Cold Case: The Tylenol Murders is available to stream on Netflix. The series offers a comprehensive look into a case that forever changed consumer trust and safety standards in the United States.